Doctors predicted that Adrienne Shapiro’s daughter Marissa would not live to see her first birthday when she was diagnosed with sickle cell disease. However, just because Marissa made it past that criterion did not mean Adrienne’s worries were over. In fact, it marked the start of a long period of painful blood transfusions and immunological problems. Marissa was unable to receive any more blood transfusions after a severe reaction caused by an improperly matched blood transfusion resulted in the removal of her gall bladder and temporary kidney failure.Learn more by visiting Kansas City regenerative medicine
Fortunately for Marissa, a clinical trial sponsored by the California Institute for Regenerative Medicine (CIRM) and led by Don Kohn, MD at UCLA was about to begin. The project’s goal was to “remove the patient’s bone marrow and correct the genetic defect in the blood-forming stem cells.” The cells can then be reintroduced into the patient, resulting in a new, healthy blood system.’ Adrienne is hopeful that, thanks to the success of this clinical trial, her daughter will be able to live a healthy and pain-free life with the help of regenerative medicine. ‘Regenerative Medicine,’ according to the Stem Cell & Regenerative Medicine Centre at the University of Wisconsin-Madison, is a “new scientific and medical discipline focused on harnessing the power of stem cells and the body’s own regenerative capabilities to restore function to damaged cells, tissues, and organs.” New-born children’s umbilical cord blood contains stem cells, which have the ability to renew and regenerate themselves. A stem cell can divide to become a specialized cell such as a brain cell or a muscle cell, or it can stay a stem cell, thanks to the process of mitosis. They can also treat any disease, disorder, or trauma that has caused internal damage. These cells are used to treat disorders and illnesses in a variety of ways, including stem cell transplantation, stem cell grafting, and regenerative medicine.